Research indicates that physical activity may have beneficial effects for several aspects of cancer survivorship specifically weight gain quality of life cancer recurrence or progression and prognosis likelihood of survival 29 30most of the evidence for the potential benefits of physical activity in cancer survivors comes from people diagnosed with breast prostate or colorectal . Select proposed mechanisms that undergird energy balance effects on cancer were addressed by experts in a recent workshop entitled the role of obesity in cancer survival and recurrence convened by the institute of medicines iom national cancer policy forum in washington dc october 31 november 1 2011. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion this volume of energy balance and cancer will focus on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. 2 inflammatory state associated with obesity and metabolic syndrome is one mechanism that promotes cancer link btw increase energy intake and cancer due to inflammation 3 1nutrient excess can trigger responses in many cell types endothelial cells hepatocytes myocytes adipocytes and macrophages. Energy balance obesity and cancer prevention the mission of this coe is to enhance knowledge regarding the association of energetics and obesity with cancer carcinogenesis from the cell to the community contribute to understanding the link between obesity and cancer and based on relevant health behavior theories provide insight about
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