Alpha 1 antitrypsin deficiency is a disease passed down from your parents that can make it hard to breathe find out about its causes symptoms diagnosis and treatment. Alpha 1 antitrypsin deficiency alpha 1 is a hereditary genetic disorder which may lead to the development of lung and or liver disease it is the most common genetic cause of liver disease in children adults can also be affected by alpha 1 and may develop lung conditions such as emphysema as well as liver problems. Alpha 1 antitrypsin aat deficiency is an inherited condition in which you do not have enough of a protein aat causing a higher risk for lung disease learn about causes risk factors screening and prevention signs and symptoms diagnoses and treatments for aat deficiency and how to participate in clinical trials. Severe deficiency of alpha 1 antitrypsin aat is associated with early onset pulmonary emphysema and with several forms of liver disease including cirrhosis neonatal hepatitis and hepatocellular carcinoma the discovery of the structure and function of the aat protein and its subsequent . Alpha 1 antitrypsin deficiency a1ad or aatd is a genetic disorder that may result in lung disease or liver disease onset of lung problems is typically between 20 and 50 years old 1 this may result in shortness of breath wheezing or an increased risk of lung infections
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